San Francisco @ Seattle
San Francisco +7 -105 over Seattle

Posted Saturday at 8:00 AM EST. Odds are subject to change.

Saturday January 17th

Lumen Field, Seattle, WA

San Francisco +7 over Seattle

8:00 PM EST. San Francisco catching a full touchdown is a classic case of perception driving price rather than matchup driving number. The market is leaning heavily on what happened in the regular-season finale and the idea that Seattle’s defense has “solved” the 49ers, but divisional playoff games rarely follow that script. These teams know each other too well, and when familiarity rises, margins tend to shrink. Getting seven points with a roster that still includes elite talent on both sides of the ball is not something long-term bettors should ignore, regardless of venue.

The narrative surrounding San Francisco is that they are battered, depleted, and hanging on by duct tape, yet that exact storyline existed last week in Philadelphia — and it never mattered to the spread. The 49ers didn’t need to be explosive; they needed to be functional, disciplined, and physical, and that’s exactly what they were. This team is built to survive ugly games, especially when they can control tempo and shorten possessions. Seattle’s defense is legitimate, but the idea that it can simply erase San Francisco again assumes everything breaks perfectly for the home side twice in a row, which is rarely how postseason football works.

From a matchup standpoint, Seattle’s offense is far less trustworthy than the public wants to admit. Whether it’s a compromised starter or a backup under center, this is not an offense built to separate from quality opponents. Sustained drives have been an issue, and explosive plays are inconsistent. San Francisco’s defense, while not flawless, is more than capable of keeping this game within one score, especially if Seattle settles into conservative game management rather than aggression. That dynamic strongly favors the underdog holding points.

Ultimately, this is about price, not prediction. Seattle may very well win the game, but asking them to clear a full touchdown against a division rival with championship-level experience is a different question entirely. San Francisco doesn’t need style points; they need to hang around, force Seattle to earn everything, and capitalize on mistakes when they come. With the market overreacting to injuries and recent results, the value sits squarely with the points.

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Our Pick

San Francisco +7 -105 (Risking 2.1 units - To Win: 2.00)

New England -4 +105 over Houston
Chicago +4 -110 over L.A. Rams